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Using mRNA to investigate the effect of low-pressure ultraviolet disinfection on the viability of

Chao Yang, Wenjun Sun, Xiuwei Ao

《环境科学与工程前沿(英文)》 2019年 第13卷 第2期 doi: 10.1007/s11783-019-1111-x

摘要:

UV can induce damages on mRNA consistently among different genes.

SOS response was more active after UV treatment.

Programmed cell death was not found to be more active after UV treatment.

关键词: UV disinfection     Viability     mRNA     SOS response     Programmed cell death    

Development of a seismic design method based on response spectra for building structures

ZHOU Xiyuan, YU Ruifang

《结构与土木工程前沿(英文)》 2007年 第1卷 第2期   页码 129-141 doi: 10.1007/s11709-007-0014-2

摘要: The assumption and problem of the mode-superposition response spectrum method in seismic design code is discussed based on a brief review of the development of the seismic design method for building structures. The scope of application for the classical damping theory is analyzed and the necessity of the research on mode-superposition method for non-classical damping is presented. The progresses on the mode superposition response spectrum theory are discussed. This includes: 1) the complex mode superposition method (in real form) for the non-classically damped linear system and the general calculation formula for the application of code; 2) the complex complete quadratic combination (CCQC) method for the non-classically damped linear system, which is based on the same assumptions as in deducing the complete quadratic combination (CQC) method which is popularly used in seismic design codes of many countries; 3) the complex complete quadratic combination with three components (CCQC3) method, which is a generalization of the CCQC method to the case of multi-components and multiple-support seismic excitations and deducing corresponding method; 4) the approach for calculation of seismic response of the non-classically damped system with overcritical damping and the calculation method of seismic response for the linear system with multiple eigenvalues; 5) the time-dependent CCQC (t) algorithm considering nonstationary earthquake ground motion; 6) an applied and effective method to solve the low order complex vector basis for the large linear non-classically damped system, which can be expediently used in practice to avoid the unknown errors coming from the forced uncoupling method; 7) bringing forward the concept of partial quadratic combination in order to reduce the calculation amount of CQC and CCQC methods, and studying the primary estimation-criterion. The reasonability and applicable scope of these methods are also briefly discussed in this paper.

关键词: generalization     classical damping     mode-superposition response     calculation formula     damping theory    

Confining pressure effect on dynamic response of high rockfill dam

Xuexing CAO, Yunlong HE, Kun XIONG,

《结构与土木工程前沿(英文)》 2010年 第4卷 第1期   页码 116-126 doi: 10.1007/s11709-010-0014-5

摘要: Studies show that the dynamic properties of rockfill are strongly dependent on the confining pressure. Therefore, confining pressure effect has become a very important factor in the seismic analysis of high rockfill dam. The relationships of dynamic shear modulus versus dynamic shear strain and damping ratio versus dynamic shear strain had been improved to a certain degree on the basic of widely used Hardin-Drnevich constitutive model in this paper. Then a new model that could consider confining pressure effect has been established. Regression analysis was carried out of the dynamic triaxial experimental data of the damming materials in the Changheba hydropower station of Sichun Province, China. The results show that, the new model can fit the test data well under various confining pressures. A corresponding computational procedure was compiled and applied in the dynamic response analysis of the Changheba Dam. Comparing the calculation results between the new constitutive model and the ordinary Hardin-Drnevich model, it can be seen that the result is conservative to some extent without considering confining pressure effect.

关键词: confining pressure effect     high rockfill dam     dynamic response     Hardin-Drnevich constitutive model    

Topology optimization of transient problem with maximum dynamic response constraint using SOAR scheme

《机械工程前沿(英文)》 2021年 第16卷 第3期   页码 593-606 doi: 10.1007/s11465-021-0636-4

摘要: This paper proposes a novel method for the continuum topology optimization of transient vibration problem with maximum dynamic response constraint. An aggregated index in the form of an integral function is presented to cope with the maximum response constraint in the time domain. The density filter solid isotropic material with penalization method combined with threshold projection is developed. The sensitivities of the proposed index with respect to design variables are conducted. To reduce computational cost, the second-order Arnoldi reduction (SOAR) scheme is employed in transient analysis. Influences of aggregate parameter, duration of loading period, interval time, and number of basis vectors in the SOAR scheme on the final designs are discussed through typical examples while unambiguous configuration can be achieved. Through comparison with the corresponding static response from the final designs, the optimized results clearly demonstrate that the transient effects cannot be ignored in structural topology optimization.

关键词: topology optimization     solid isotropic material with penalization     transient response     aggregation function     second-order Arnoldi reduction    

Dynamic response of precast segmental bridge columns under heavy truck impact

《结构与土木工程前沿(英文)》 2023年 第17卷 第3期   页码 327-349 doi: 10.1007/s11709-023-0911-z

摘要: Considering the wide application of precast segmental bridge columns (PSBCs) in engineering practice, impact-resistant performance has gained significant attention. However, few studies have focused on PSBCs subjected to high-energy impacts caused by heavy truck collisions. Therefore, the behavior of PSBCs under a heavy truck impact was investigated in this study using high-fidelity finite element (FE) models. The detailed FE modeling methods of the PSBCs and heavy trucks were validated against experimental tests. The validated modeling methods were employed to simulate collisions between PSBCs and heavy trucks. The simulation results demonstrated that the engine and cargo caused two major peak impact forces during collision. Subsequently, the impact force, failure mode, displacement, and internal force of the PSBCs under heavy truck impacts were scrutinized. An extensive study was performed to assess the influence of the section size, truck weight, impact velocity, and number of precast segments on the impact responses. The truck weight was found to have a minor effect on the engine impact force. Damage was found to be localized at the bottom of the three segments, with the top remaining primarily undamaged. This parametric study demonstrated that larger cross-sections may be a preferred option to protect PSBCs against the impact of heavy trucks.

关键词: precast segmental bridge columns     heavy truck     collision     dynamic response    

Dynamic response surface methodology using Lasso regression for organic pharmaceutical synthesis

《化学科学与工程前沿(英文)》 2022年 第16卷 第2期   页码 221-236 doi: 10.1007/s11705-021-2061-y

摘要: To study the dynamic behavior of a process, time-resolved data are collected at different time instants during each of a series of experiments, which are usually designed with the design of experiments or the design of dynamic experiments methodologies. For utilizing such time-resolved data to model the dynamic behavior, dynamic response surface methodology (DRSM), a data-driven modeling method, has been proposed. Two approaches can be adopted in the estimation of the model parameters: stepwise regression, used in several of previous publications, and Lasso regression, which is newly incorporated in this paper for the estimation of DRSM models. Here, we show that both approaches yield similarly accurate models, while the computational time of Lasso is on average two magnitude smaller. Two case studies are performed to show the advantages of the proposed method. In the first case study, where the concentrations of different species are modeled directly, DRSM method provides more accurate models compared to the models in the literature. The second case study, where the reaction extents are modeled instead of the species concentrations, illustrates the versatility of the DRSM methodology. Therefore, DRSM with Lasso regression can provide faster and more accurate data-driven models for a variety of organic synthesis datasets.

关键词: data-driven modeling     pharmaceutical organic synthesis     Lasso regression     dynamic response surface methodology    

一种基于描述逻辑的体系质量需求建模与验证方法 Article

Qing-long WANG,Zhi-xue WANG,Ting-ting ZHANG,Wei-xing ZHU

《信息与电子工程前沿(英文)》 2017年 第18卷 第3期   页码 346-361 doi: 10.1631/FITEE.1500309

摘要: 在体系顶层设计问题中,体系质量需求分析的关键是体系需求的建模以及自动验证,需要合适的建模方法来描述体系质量需求以及验证质量需求是否满足体系的能力需求。针对体系质量需求建模和验证问题,本文提出一种基于描述逻辑的体系质量需求建模与验证方法。首先,为解决体系功能和非功能需求的描述问题,通过添加模糊构造子扩展统一建模语言(Unified Modeling Language, UML)中的类和关系并定义了基于元模型的领域特定建模语言以实现体系质量需求中模糊和不确定概念的建模。随后提出了基于云模型的体系质量需求评估方法实现了对体系质量需求的评估。然后,提出了模型转换算法将模糊UML构建的体系需求模型转换为描述逻辑本体模型,并通过使用描述逻辑本体推理工具实现需求模型的自动化验证。最后,通过一个案例验证和演示了本文方法的正确性和可行性。

关键词: 体系;云模型;描述逻辑;需求验证    

Persistence of humoral and cellular immune response after SARS-CoV-2 infection: opportunities and challenges

Tangchun Wu

《医学前沿(英文)》 2020年 第14卷 第6期   页码 816-819 doi: 10.1007/s11684-020-0823-4

Applications of thermostatically controlled loads for demand response with the proliferation of variable

Meng SONG, Wei SUN

《能源前沿(英文)》 2022年 第16卷 第1期   页码 64-73 doi: 10.1007/s11708-021-0732-5

摘要: More flexibility is desirable with the proliferation of variable renewable resources for balancing supply and demand in power systems. Thermostatically controlled loads (TCLs) attract tremendous attentions because of their specific thermal inertia capability in demand response (DR) programs. To effectively manage numerous and distributed TCLs, intermediate coordinators, e.g., aggregators, as a bridge between end users and dispatch operators are required to model and control TCLs for serving the grid. Specifically, intermediate coordinators get the access to fundamental models and response modes of TCLs, make control strategies, and distribute control signals to TCLs according the requirements of dispatch operators. On the other hand, intermediate coordinators also provide dispatch models that characterize the external characteristics of TCLs to dispatch operators for scheduling different resources. In this paper, the bottom-up key technologies of TCLs in DR programs based on the current research have been reviewed and compared, including fundamental models, response modes, control strategies, dispatch models and dispatch strategies of TCLs, as well as challenges and opportunities in future work.

关键词: thermostatically controlled load     demand response     renewable energy     power system operation    

Modeling of dynamic response of poroelastic soil layers under wave loading

Mehmet Bar?? Can üLKER

《结构与土木工程前沿(英文)》 2014年 第8卷 第1期   页码 1-18 doi: 10.1007/s11709-014-0233-2

摘要: In this paper, the dynamic response of saturated and layered soils under harmonic waves is modeled using the finite element method. The numerical results are then verified by corresponding analytical solutions which are also developed by the author. The equations governing the dynamics of porous media are written in their fully dynamic form and possible simplifications are introduced based on the presence of inertial terms associated with solid and fluid phases. The response variations are presented in terms of pore water pressure and shear stress distributions within the layers. It is determined that a set of non-dimensional parameters and their respective ratios as a result of layering play a major role in the dynamic response.

关键词: dynamic response of soils     coupled flow-deformation     finite elements     analytical solution     harmonic waves    

Seismic response reduction of a three-story building by an MR grease damper

Tomoki SAKURAI, Shin MORISHITA

《机械工程前沿(英文)》 2017年 第12卷 第2期   页码 224-233 doi: 10.1007/s11465-017-0413-6

摘要:

This paper describes an application of magneto-rheological (MR) grease dampers as seismic dampers for a three-story steel structure. MR fluid is widely known as a smart material with rheological properties that can be varied by magnetic field strength. This material has been applied to various types of devices, such as dampers, clutches, and engine mounts. However, the ferromagnetic particles dispersed in MR fluid settle out of the suspension after a certain interval because of the density difference between the particles and their carrier fluid. To overcome this defect, we developed a new type of controllable working fluid using grease as the carrier of magnetic particles. MR grease was introduced into a cylindrical damper, and the seismic performance of the damper was subsequently studied via numerical analysis. The analysis results of the MR grease damper were compared with those of other seismic dampers. We confirmed that the MR grease damper is an effective seismic damper.

关键词: MR grease damper     seismic damper     vibration control     structural response     FEM analysis    

Demand response based congestion management in a mix of pool and bilateral electricity market model

Ashwani KUMAR, Charan SEKHAR

《能源前沿(英文)》 2012年 第6卷 第2期   页码 164-178 doi: 10.1007/s11708-012-0187-9

摘要: The independent system operator (ISO) is a key element in the deregulated structure with one of the responsibilities of transmission congestion management (CM). The ISO opts market based solutions to manage congestion receiving bids from generation companies (GENCOs) as well as distribution companies (DISCOMs) to reschedule their generation and relocate demand. The nodal prices increases during the congestion hours and the demand response to nodal prices will be an effective tool for the control of congestion. In this paper, demand response-based CM has been proposed for a mix of pool and bilateral electricity market model. The linear bid curves have been considered for demand bids to respond to the congestion in the network. The bilateral demand has been obtained with minimum deviations in their preferred schedule. The impact of flexible alternating current transmission system (FACTS) devices viz static var compensator (SVC) and thyristor controlled series compensator (TCSC) has also been considered for demand management during congestion. Multi-line congestion cases have been considered to study the impact on demand response without and with FACTS devices. The proposed approach has been tested on the IEEE 24 bus test system.

关键词: bid function     congestion management (CM)     demand response     pool+bilateral electricity market     static var compensator (SVC)     thyristor controlled series compensator (TCSC)    

Influence of site conditions on seismic design parameters for foundations as determined via nonlinear site response

Muhammad Tariq A. CHAUDHARY

《结构与土木工程前沿(英文)》 2021年 第15卷 第1期   页码 275-303 doi: 10.1007/s11709-021-0685-0

摘要: Site conditions, including geotechnical properties and the geological setting, influence the near-surface response of strata subjected to seismic excitation. The geotechnical parameters required for the design of foundations include mass density ( ), damping ratio ( ), shear wave velocity ( ), and soil shear modulus ( ). The values of the last three parameters are sensitive to the level of nonlinear strain induced in the strata due to seismic ground motion. In this study, the effect of variations in soil properties, such as plasticity index ( ), effective stress ( ), over consolidation ratio (OCR), impedance contrast ratio ( ) between the bedrock and the overlying strata, and depth of soil strata over bedrock ( ), on seismic design parameters ( , , and ) was investigated for National Earthquake Hazards Reduction Program (NEHRP) site classes C and D, through 1D nonlinear seismic site response analysis. The Morris one-at-a-time (OAT) sensitivity analysis indicated that , , and were significantly influenced by variations in , while affected more than it affected and . However, the influence of on these parameters was less significant. It was also found that variations in soil properties influenced seismic design parameters in soil type D more significantly than in soil type C. Predictive relationships for , , and were derived based on the 1D seismic site response analysis and sensitivity analysis results. The , , and values obtained from the analysis were compared with the corresponding values in NEHRP to determine the similarities and differences between the two sets of values. The need to incorporate and in the metrics for determining , , and for the seismic design of foundations was highlighted.

关键词: site effects     1D seismic site response analysis     sensitivity analysis     foundations     shear wave velocity     soil shear modulus    

Numerical study on the seismic response of the underground subway station- surrounding soil mass-ground

Guobo WANG, Mingzhi YUAN, Xianfeng MA, Jun WU

《结构与土木工程前沿(英文)》 2017年 第11卷 第4期   页码 424-435 doi: 10.1007/s11709-016-0381-7

摘要: Ground buildings constructed above metro station have increased very quickly due to the limited land resources in urban areas. In this paper, the seismic response of the Underground subway station-Surrounding soil mass-Ground adjacent buildings (USG) system subjected to various seismic loading is studied through numerical analysis. The numerical model is established in terms of the calculation domain, boundary condition, and contact property between soil and structure based on the real project. The reciprocal influence between subway station and ground adjacent building, and their effects on the dynamic characteristics of surrounding soil mass are also investigated. Through the numerical study, it is found that the impact of underground structure on the dynamic characteristics of the surrounding soil mass depends on its own dimension, and the presence of underground structure has certain impact on the seismic response of ground adjacent building. Due to the presence of underground structure and ground adjacent building, the vertical acceleration generated by the USG system cannot be ignored. The outcomes of this study can provide the references for seismic design of structures in the USG system.

关键词: underground subway station     ground adjacent building     seismic response    

Finite element modeling of cable sliding and its effect on dynamic response of cable-supported truss

Yujie YU, Zhihua CHEN, Renzhang YAN

《结构与土木工程前沿(英文)》 2019年 第13卷 第5期   页码 1227-1242 doi: 10.1007/s11709-019-0551-5

摘要: The cable system of cable-supported structures usually bears high tension forces, and clip joints may fail to resist cable sliding in cases of earthquake excitations or sudden cable breaks. A analytical method that considers the dynamic cable sliding effect is proposed in this paper. Cable sliding behaviors and the resultant dynamic responses are solved by combining the vector form intrinsic finite element framework with cable force redistribution calculations that consider joint frictions. The cable sliding effect and the frictional tension loss are solved with the original length method that uses cable length and the original length relations. Then, the balanced tension distributions are calculated after frictional sliding. The proposed analytical method is achieved within MATLAB and applied to simulate the dynamic response of a cable-supported plane truss under seismic excitation and sudden cable break. During seismic excitations, the cable sliding behavior in the cable-supported truss have an averaging effect on the oscillation magnitudes, but it also magnifies the internal force response in the upper truss structure. The slidable cable joints can greatly reduce the ability of a cable system to resist sudden cable breaks, while strong friction resistances at the cable-strut joints can help retain internal forces.

关键词: sliding cable     explicit solution framework     original length method     seismic response     cable rupture    

标题 作者 时间 类型 操作

Using mRNA to investigate the effect of low-pressure ultraviolet disinfection on the viability of

Chao Yang, Wenjun Sun, Xiuwei Ao

期刊论文

Development of a seismic design method based on response spectra for building structures

ZHOU Xiyuan, YU Ruifang

期刊论文

Confining pressure effect on dynamic response of high rockfill dam

Xuexing CAO, Yunlong HE, Kun XIONG,

期刊论文

Topology optimization of transient problem with maximum dynamic response constraint using SOAR scheme

期刊论文

Dynamic response of precast segmental bridge columns under heavy truck impact

期刊论文

Dynamic response surface methodology using Lasso regression for organic pharmaceutical synthesis

期刊论文

一种基于描述逻辑的体系质量需求建模与验证方法

Qing-long WANG,Zhi-xue WANG,Ting-ting ZHANG,Wei-xing ZHU

期刊论文

Persistence of humoral and cellular immune response after SARS-CoV-2 infection: opportunities and challenges

Tangchun Wu

期刊论文

Applications of thermostatically controlled loads for demand response with the proliferation of variable

Meng SONG, Wei SUN

期刊论文

Modeling of dynamic response of poroelastic soil layers under wave loading

Mehmet Bar?? Can üLKER

期刊论文

Seismic response reduction of a three-story building by an MR grease damper

Tomoki SAKURAI, Shin MORISHITA

期刊论文

Demand response based congestion management in a mix of pool and bilateral electricity market model

Ashwani KUMAR, Charan SEKHAR

期刊论文

Influence of site conditions on seismic design parameters for foundations as determined via nonlinear site response

Muhammad Tariq A. CHAUDHARY

期刊论文

Numerical study on the seismic response of the underground subway station- surrounding soil mass-ground

Guobo WANG, Mingzhi YUAN, Xianfeng MA, Jun WU

期刊论文

Finite element modeling of cable sliding and its effect on dynamic response of cable-supported truss

Yujie YU, Zhihua CHEN, Renzhang YAN

期刊论文